Endothelial Dysfunction Simplified – What You Need To Know

Endothelial Process

Making a complicated subject uncomplicated: Endothelial Dysfunction.

Endothelial Dysfunction is what causes Type 2 Diabetes, Cardiovascular Disease (Atherosclerosis), Erectile Dysfunction, Inflammatory Conditions, and Aneurysms.

(Rear more about Erectile Dysfunction here: ‘Erectile Dysfunction, Cardiovasular Disease and Diet’).

Basic Definition: When the paper thin lining (endothelial cells) of your blood vessels and heart become damaged.

Cause: Too much saturated fat, not enough nitric oxide (fruits and veggies).

The good thing is that as long as you have not done too much damage – the above conditions are completely REVERSIBLE with a Plant-Based Diet.

Take control of your health, Go Plant Based!

Read about my weight loss and health improvement along with easy weight loss tips here.

If you have Type 2 Diabetes and you would like to know how to reverse it, click here.

Extensive Reading:

If you would like to read more extensive research on Endothelial Dysfunction read this paper for reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315380/

Study Abstract:

A plant-based diet is increasingly becoming recognized as a healthier alternative to a diet laden with meat. Atherosclerosis associated with high dietary intake of meat, fat, and carbohydrates remains the leading cause of mortality in the US. This condition results from progressive damage to the endothelial cells lining the vascular system, including the heart, leading to endothelial dysfunction. In addition to genetic factors associated with endothelial dysfunction, many dietary and other lifestyle factors, such as tobacco use, high meat and fat intake, and oxidative stress, are implicated in atherogenesis. Polyphenols derived from dietary plant intake have protective effects on vascular endothelial cells, possibly as antioxidants that prevent the oxidation of low-density lipoprotein. Recently, metabolites of L-carnitine, such as trimethylamine-N-oxide, that result from ingestion of red meat have been identified as a potential predictive marker of coronary artery disease (CAD). Metabolism of L-carnitine by the intestinal microbiome is associated with atherosclerosis in omnivores but not in vegetarians, supporting CAD benefits of a plant-based diet. Trimethylamine-N-oxide may cause atherosclerosis via macrophage activation. We suggest that a shift toward a plant-based diet may confer protective effects against atherosclerotic CAD by increasing endothelial protective factors in the circulation while reducing factors that are injurious to endothelial cells. The relative ratio of protective factors to injurious endothelial exposure may be a novel approach to assessing an objective dietary benefit from a plant-based diet. This review provides a mechanistic perspective of the evidence for protection by a plant-based diet against atherosclerotic CAD.

2 Replies to “Endothelial Dysfunction Simplified – What You Need To Know

  1. Hello There. I found your blog using msn. This is a really well written article. Thanks for the post. I will definitely return.

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